Feasibility of Producing Molybdenum-99 on a Small Scale Using Fission of Low Enriched Uranium or Neutron Activation of Natural Molybdenum
|Classification||6.07.4.60/32 (MISCELLANEOUS - NUCLEAR MEDICINE / MEDICAL APPLICATIONS - RADIO ISOTOPES)|
From the publication:
Feasibility of Producing Molybdenum-99 on a Small Scale Using Fission of Low Enriched Uranium or Neutron Activation of Natural Molybdenum INTERNATIONAL ATOMIC ENERGY AGENCY VIENNA, 2015 IAEA Technical reports series no. 478 FOREWORD This publication documents the work performed within the IAEA coordinated research project (CRP) on Developing Techniques for Small Scale Indigenous Molybdenum-99 Production Using LEU Fission or Neutron Activation. The project allowed participating institutions to receive training and information on aspects necessary for starting production of molybdenum-99 (99Mo) on a small scale, that is, to become national level producers of this medical isotope. Stable production of 99Mo is one of the most pressing issues facing the nuclear community at present, because the medical isotope technetium-99m (99mTc), which decays from 99Mo, is one of the most widely used radionuclides in diagnostic imaging and treatment around the world. In the past five years, there have been widespread shortages of 99Mo owing to the limited number of producers, many of which use ageing facilities. To assist in stabilizing the production of 99Mo, and to promote the use of production methods that do not rely on the use of highly enriched uranium (HEU), the IAEA initiated the abovementioned CRP on small scale 99Mo production using low enriched uranium (LEU) fission or neutron activation methods. The intention was to enable participating institutions to gain the knowledge necessary to become national level producers of 99Mo in the event of further global shortages. Some of the institutions that participated in the CRP have continued their work on 99Mo production, and are enlisting the assistance of other CRP members and the IAEA’s technical cooperation programme to set up a small scale production capability.