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Publication Laka-library:
Enhancement of biological response to internal sequential beta emitters from 2nd event effects

AuthorC.Busby, I.House, Mallwyd
Date
Classification 6.01.4.80/22 (RADIATION - DISCUSSION ON LOW-LEVEL RADIATION)
Front

From the publication:

Sir,

It is now well established that, for low doses of ionizing radiation of various sorts
(Miller et.al. 1979, Elkind 1991), split doses can have a greater biological effect
at low dose than the same overall dose given singly, It cannot be disputed that the
target of these effects must be single cell nuclei and it is probable that it is the
cellular repair and replication processes which are being perturbed in some way.
Whatever the cause of such effects, it is an interesting consequence that similar
effects to those found in in vitro studies using external irradiation by e.g. X-rays
may be expected from sequentially decaying internal beta emitters and also alpha
emitters under certain circumstances.

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